He isn't on good terms with Ramiris. From the very moment they met, he had thought to kill her a few times.
She is a childhood friend of Leon, a best friend. An existence he loved like a sister, his everything.
A good friend, Despite Guy's advances towards him.
Rimuru initially disliked him because of treatment of Shizue but after realizing that he actually, in fact, saved the latter's life, Rimuru cooperated with him. They also cooperated with one another several times. He fully trusts that he can leave Chloe in Rimuru's hands. During the Great Tenma War, he evolved into a Demi-God when Rimuru reconstructed his core to revive him.